Galectin-4 and Small Intestinal Brush Border Enzymes Form Clusters
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چکیده
منابع مشابه
Fetal Forms of Enzymes of Intestinal Brush Border
The surface membrane of the small intestine comes into contact with luminal nutrients, organisms, drugs and foreign antigens. The natural frontier between the body and the intestinal content is represented by the glycoproteins of the brush border membrane, which act as receptors, carriers and hydrolytic enzymes. Developmental variability of these glycoproteins may therefore regulate intestinal ...
متن کاملShaping the intestinal brush border
Epithelial cells from diverse tissues, including the enterocytes that line the intestinal tract, remodel their apical surface during differentiation to form a brush border: an array of actin-supported membrane protrusions known as microvilli that increases the functional capacity of the tissue. Although our understanding of how epithelial cells assemble, stabilize, and organize apical microvill...
متن کاملRat Intestinal Brush Border Membrane Peptidases
The properties of two purified peptidases derived from the intestinal brush border membrane of the rat have been investigated. The pH optima, heat stabilities, substrate specificities, and metal ion requirements of the two enzymes and the effects of inhibitors on their activities were nearly identical. The isoenzymes catalyzed the hydrolysis of a wide range of peptides containing from 2 to 8 am...
متن کاملEffects of urogastrone-epidermal growth factor on intestinal brush border enzymes and mitotic activity.
The wet weight of the stomach, small intestine, caecum, and colon were significantly reduced (p less than 0.001) in intravenously fed rats compared with orally fed controls. Human epidermal growth factor (urogastrone) reversed this atrophy. Detailed analysis of the small intestine showed a similar effect on intestinal crypt cell population, mitoses per crypt, and protein content. Brush border g...
متن کاملActivities of gastric, pancreatic, and intestinal brush-border membrane enzymes during postnatal development of dogs.
OBJECTIVE To measure activities of digestive enzymes during postnatal development in dogs. SAMPLE POPULATION Gastrointestinal tract tissues obtained from 110 Beagles ranging from neonatal to adult dogs. PROCEDURE Pepsin and lipase activities were measured in gastric contents, and amylase, lipase, trypsin, and chymotrypsin activities were measured in small intestinal contents and pancreatic ...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 1997
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.8.11.2241